You may be asking a funny question, yet the science behind it is real. Some chemicals can change a spider’s behavior enough that it looks like the spider is “high,” but that is not the same as a human-style high.
In lab tests, researchers have used spider webs as a visible clue that a substance has affected the animal’s nervous system.

When you ask, “can you get spiders high,” the short answer is yes, in a limited scientific sense. Spiders can get high enough for their movement, web-building, and coordination to change in obvious ways.
That makes them useful for studying how chemicals affect living systems.
The Short Answer: How Chemicals Affect Spiders

Chemicals can shift spider behavior by interfering with the systems that control movement, timing, and web design. Scientists use those visible changes to study spider behavior and compare how different substances affect the same basic instinct.
What Scientists Mean By Altered Behavior
When scientists say a spider is altered, they mean its normal actions look different after exposure to a chemical. The spider may move oddly, stop early while building, or produce a web with missing sections.
That does not prove a human-like feeling of intoxication. It does show that the spider’s nervous system has changed.
Why Web-Building Reveals Nervous System Disruption
Web-building is a repeatable task, so small changes stand out fast. A healthy spider usually builds a neat, structured web.
A disrupted spider may leave gaps, crooked lines, or weak symmetry. Web shape works like a visible record of nervous system stress.
Researchers have used spider-web patterns to determine toxicity.
What The Spider-Web Experiments Found
Spider web studies became famous because the results were easy to see and compare. Researchers noticed that different chemicals did not just make webs “bad,” they changed the web patterns in specific ways.
Peter Witt’s Early Drug Studies
Peter Witt was one of the first scientists to test how drugs affected web building. He worked with spiders and studied compounds such as caffeine, marijuana, and LSD, looking for changes in spider web patterns.
His work showed that using spider-web patterns to determine toxicity could reveal nervous system effects without complicated equipment.
NASA’s 1995 Web Analysis Results
NASA also studied spider webs as a way to judge chemical toxicity. In 1995, NASA released a technical briefing that focused on how different substances changed web structure.
If a chemical changes the web, it likely changes the spider’s internal control systems too.
How Caffeine, Marijuana, LSD, And Benzedrine Changed Webs
Different substances produced different web changes. According to research summaries of these studies, caffeine often made webs messy and disorganized.
Marijuana and THC could leave webs more symmetrical but incomplete. LSD caused strong disruption that sometimes led to tangled or unusable webs.
Benzedrine and similar stimulants also changed building behavior. Spiders did not react the same way to every drug.
Those differences made the experiments useful for comparing how chemicals affect spider web patterns.
What Web Changes Can And Cannot Prove
A changed web can tell you that a spider’s nervous system changed, but it cannot tell you exactly what the spider feels. Spider behavior is easy to observe, while spider experience is much harder to measure.
Why Distorted Webs Suggest Impairment
A distorted web suggests impairment because web building depends on timing, movement, and spatial control. When those systems are off, the web often shows it right away through bad symmetry, missing threads, or strange shapes.
Web changes are a strong sign that a substance disrupted the spider’s body or brain. It does not require guesswork to see that something went wrong.
Limits Of Comparing Spider Reactions To Human Intoxication
You should not compare a spider’s reaction too closely with your own.
Spiders do not have human emotions.
A changed web does not prove the spider feels pleasure, confusion, or a recreational high.
Science shows that chemicals change arachnid behavior.
The safest answer to “can spiders get high” is that they can show drug-induced impairment, not a human-style high.