Cushing’s disease is a serious condition that can affect your Border Terrier, and it’s important to recognize its signs. Your dog’s adrenal glands produce too much cortisol, a hormone that helps manage stress and metabolism. Increased cortisol levels can lead to symptoms such as excessive thirst, frequent urination, and changes in appetite.

If you notice your Border Terrier showing any unusual behaviors or health issues, it could indicate Cushing’s disease. This condition is more common in older dogs, so being aware of its symptoms can help you catch it early.
Proper diagnosis and treatment can greatly improve your dog’s quality of life.
Understanding Cushing’s disease can feel overwhelming, but you can make a difference for your furry friend. Staying informed about this endocrine disorder allows you to seek timely veterinary care for your beloved pet and ensure they receive the best support.
Understanding Cushing’s Disease in Dogs

Cushing’s disease can be a serious concern for dog owners. It involves the overproduction of cortisol, affecting vital functions in your dog’s body. Recognizing how this condition develops and the roles of specific glands will help you understand its impact.
Overview of Cushing’s Syndrome
Cushing’s syndrome, also known as hyperadrenocorticism, occurs when there’s too much cortisol in your dog’s system. Symptoms may include increased thirst, frequent urination, and a pot-bellied appearance. These signs can be subtle at first, making it essential to monitor your dog’s behavior.
Diagnosis usually starts with blood tests or urinalysis. Cushing’s disease is often diagnosed in middle-aged to older dogs, including Border Terriers. Recognizing early symptoms will help you seek veterinary assistance sooner, ensuring your dog gets the proper care.
The Role of The Adrenal Glands
The adrenal glands are small organs located on top of each kidney. They produce hormones, including cortisol, which manage stress responses, metabolism, and immune function. When these glands produce excess cortisol, it leads to Cushing’s disease.
Cushing’s can arise from different issues affecting the adrenal glands. In many cases, a problem with the pituitary gland causes the adrenal glands to overproduce cortisol. This connection is crucial, as it helps veterinarians determine the appropriate treatment for your dog.
Types of Cushing’s Disease
Cushing’s disease can be classified into three main types:
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Pituitary-Dependent: This is the most common type. A tumor in the pituitary gland signals the adrenal glands to produce excess cortisol.
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Adrenal-Dependent: This type involves a tumor on one or both adrenal glands that causes increased cortisol production.
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Iatrogenic: This occurs when dogs receive excessive corticosteroids for other medical conditions. Reducing the medication gradually can help these dogs recover.
Understanding these types will help you work with your veterinarian to determine an effective treatment plan for your Border Terrier. Each case is unique, and your vet will guide you on the best path forward.
Recognizing the Signs and Symptoms

When it comes to Cushing’s disease in Border Terriers, being aware of the signs and symptoms is essential. Early recognition can lead to timely veterinary care, which can improve your dog’s quality of life.
Common Clinical Signs
You may notice several noticeable symptoms if your Border Terrier has Cushing’s disease. Increased thirst and increased urination are typical early signs. Your dog might drink more water than usual and need to go outside more often.
Another common sign is increased appetite. This can lead to significant weight gain, even if your dog isn’t getting extra food. You might see your pet panting more frequently, which could indicate discomfort.
Watch for any changes in energy levels. Lethargy is another concern. If your dog seems less active or spends more time resting, it’s important to consult your vet. Skin infections and cataracts can also occur, which are worth mentioning during your visit.
Behavioral Changes
Cushing’s disease can affect your Border Terrier’s behavior too. You might notice your pet is more irritable or anxious than usual. This change may be linked to discomfort from physical symptoms.
Sometimes, you may see signs of restlessness. Your dog might have trouble settling down at night or appear agitated during the day. Increased appetite can sometimes lead to pacing as your dog looks for food.
There’s also a risk of urinary tract infections. Increased urination can lead to irritation, causing your dog to act uncomfortable. If you observe any sudden changes in behavior, it’s wise to discuss these with your vet right away.
Diagnosis and Testing

Diagnosing Cushing’s disease in Border Terriers involves several key tests to confirm the presence of the condition. These tests help your veterinarian understand more about your dog’s health and hormone levels.
ACTH Stimulation Test
The ACTH stimulation test measures how your dog’s adrenal glands respond to adrenocorticotropic hormone (ACTH). Your vet will first take a blood sample to check the baseline cortisol level. Then, they will administer an injection of synthetic ACTH and take another blood sample 1-2 hours later.
If the cortisol levels rise significantly after the injection, it may indicate Cushing’s disease. This test is useful for determining if the adrenal glands are overactive. It can also help differentiate between Cushing’s and other conditions that affect cortisol levels.
Low Dose Dexamethasone Suppression Test
In the low dose dexamethasone suppression test, your vet will give your dog a small dose of a medication called dexamethasone. This steroid normally suppresses cortisol production. Blood samples will be taken at specific intervals to measure cortisol levels before and after the dexamethasone is given.
If your dog has Cushing’s disease, the cortisol levels will remain high even after the medication. This test can help identify the type of Cushing’s disease, distinguishing between pituitary-dependent and adrenal tumors, which can be crucial for treatment planning.
Imaging Tests
Imaging tests, such as abdominal ultrasound, provide a visual assessment of your dog’s internal organs. These tests can help identify any tumors on the adrenal glands or other abnormalities.
Your vet may recommend these tests if they suspect an adrenal tumor. Finding a tumor early can greatly influence treatment decisions. Imaging can also help ensure that any blood clots or other complications are not present, allowing for a more accurate diagnosis and effective management of your dog’s health.
Treatment Options and Management

Managing Cushing’s disease in Border Terriers involves various treatment options tailored to your dog’s specific needs. You can use medications, consider surgery, and make lifestyle modifications to improve your pet’s quality of life.
Medication
One common treatment is medication like Vetoryl (trilostane). This drug helps lower cortisol levels in the body. Your vet will monitor your dog’s response to the medication carefully, as it can take a little time to find the right dosage.
Regular blood tests are crucial to check cortisol levels and adjust treatment as needed. In many cases, dogs respond well to medication, leading to an improved quality of life. Always keep an eye out for side effects, such as vomiting or diarrhea, and inform your vet if they occur.
Surgery
In some cases, surgical options like adrenalectomy may be recommended, especially if a tumor is causing excessive cortisol production. This procedure involves removing the affected adrenal gland.
While surgery can be effective, it does come with risks. Your veterinarian will help you weigh the pros and cons based on your dog’s health. In some cases, radiation therapy may also be considered to target tumors causing Cushing’s disease. Always consult with your vet about the best approach for your furry friend.
Lifestyle Modifications
Making lifestyle changes can also support your dog’s health.
Establishing a balanced diet is crucial. Focus on high-quality dog food that meets your Border Terrier’s nutritional needs. Discuss any necessary dietary changes with your vet.
Regular exercise is also important. It helps maintain a healthy weight and improves overall well-being.
Aim for daily walks and playtime suited to your dog’s energy levels. Avoid strenuous activities, especially if your dog shows signs of fatigue.
By combining medication, surgery, and lifestyle modifications, you can help manage Cushing’s disease and enhance your Border Terrier’s quality of life.